Compare the Structure and Function of Collagen and Haemoglobin Essay

Haemoglobin is a transport protein that carries oxygen from the lungs to the tissues and carries blow dioxide from the tissues back to the lungs. In order to function most efficiently, hemoglobin require to bind to oxygen tightly when the oxygen concentration is high in the lungs and be able to release oxygen rapidly in the comparatively low partial pressure in the tissues. I will be comparing the organize and function of hemoglobin with the social system and function of collagen, which is a structural protein. Collagens functions be quite discordent from those of globular proteins such as enzymes tough bundles of collagen called collagen fibers are a major component of the extracellular matrix that supports most tissues and softens cells structure from the exposeside. Collagen is also show up in trustworthy cells as it has great tensile military unit, and is the main component of fascia, cartilage, ligaments, tendons, bone and teeth. uncomplicated feather Structure t he number, type and sequence of amino acidsThe primary level of structure in a protein is the linear sequence of amino acids, formed by a condensation reaction. The primary structure of these proteins are very different. The haemoglobin molecule consists of quadruple-spot polypeptide (globin) custody, where as collagen is made up of three polypeptide chains wound round severally other. In Haemoglobin there are a wide range of amino acid constituents in the primary structure, in contrast 35% of collagens primary structure is glycine. This dissimilitude in primary structure causes the proteins themselves to be different due to the passe-partout different primary structure the haemoglobin protein is soluble in piddle whereas the collagen protein is not.Secondary structure Formed when the chain of amino acid coils or folds to form an alpha helix or important pleated sheet. Haemoglobin is comprised of four polypeptide subunits, two with alpha helix secondary structure and two with beta pleated sheet form. All four components carry a heme host that can bind to oxygen, and all four components must be present to form haemoglobin. The shape of the haemaglobin affects its ability to carry oxygen, and travel freely end-to-end the circulatory system. Whereas Collagens secondary structure involves three strands of protein bonded together amongst the chains with hydrogen bonds and then twisted into a helix that is referred to as a collagen helix.Tertiary structure the final three dimensional shape of protein is formed when these coils and pleats coil or fold. Due to interactions between R-groups of the different amino acids. The tertiary structure or overall shape of collagen protein subunits is a helical chain. Due to the ways in which the amino acids are set the protein can be hydrophobic or hydrophilic. Soluble proteins, like haemoglobin will fold with the hydrophobic side on the inside and the hydrophilic side on the outside. As with all proteins th e tertiary structure of each subunit is held in place by a number of bonds and interactions, these interation give the subunits and whole molecule very specific shapes, this is why haemoglobin and collagen differ so greatly in structure and in function as the shape of the molecule (due to the tertiary structure) is vital for the molecule to carry out its function.Quaternary structure some proteins are made up of much than one polypeptide subunit joined together.  The quaternary structure of haemoglobin consists of four polypeptide subunits. Two are called alpha chains and two are called beta chains. The four subunits together form one haemoglobin molecule, which is water soluble. In comparison, The quaternary structure of collagen consists of three left-handed helices twisted into a dextral coil. Fibrous proteins, like collagen contain polypeptide chains arranged in want strands or sheets, whereas globular proteins, like haemoglobin have polypeptide chains that are folded in a spherical shape.Due to the differences in structure of collagen and haemoglobin their shape and function also differ greatly. The triple helix structure of collagen gives the structure strength and therefore the function of collagen is to provide mechanical strength in many areas. Where as the presence of a prosthetic group, Haem, in the structure of haemoglobin pith oxygen can bind to the iron. This means that one complete haemoglobin molecule can bind up to four